How to enable/disable HubTile rotation transition in runtime?

You can achieve it by setting HubTile TileType property as DefaultType, so that rotation transition will be disabled.

// Sets HubTile as Default Tile and Rotation will be disabled
this.RotateTile.TileType = HubTileType.DefaultTile;
'Sets HubTile as Default Tile and Rotation will be disabled
Me.RotateTile.TileType = HubTileType.DefaultTile